
Brooks Glycerin 21
by Brooks
The Brooks Glycerin 21 continues the line's reputation as one of the most plush, comfortable neutral running shoes available, ideal for runners prioritizing maximum cushioning and all-day comfort over speed.
- Ultra-plush cushioning
- All-day comfort
- Smooth ride transition
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The Brooks Glycerin 21 continues the line's reputation as one of the most plush, comfortable neutral running shoes available, ideal for runners prioritizing maximum cushioning and all-day comfort over speed.
Key features
- DNA Loft v3 cushioning midsole
- Engineered air mesh upper
- Plush internal tongue and collar
- Segmented crash pad outsole
- Neutral support running shoe design
Pros & cons
PROS What we loved
- Extremely soft, cloud-like cushioning
- Breathable and soft engineered mesh upper
- Smooth heel-to-toe transition
- Comfortable for long-distance and daily runs
- Roomy toe box
CONS Worth noting
- Higher price point
- Slightly heavier than performance trainers
- Cushioning may feel too soft for speed workouts
Specifications
Full review
The Brooks Glycerin 21 is a premium neutral running shoe built for runners who crave plush, cushioned comfort on every mile without sacrificing a smooth, responsive ride. At the heart of this shoe is Brooks' updated nitrogen-infused DNA LOFT v3 midsole, offering a softer, lighter, and more resilient cushioning experience than previous iterations. This foam technology adapts to your stride, delivering a pillowy landing while still providing the energetic bounce needed to propel you forward, making it an excellent choice for long runs, daily training, or simply all-day wear where comfort is paramount.
Designed with a refined engineered mesh upper, the Glycerin 21 wraps the foot in a breathable, adaptive fit that moves with you mile after mile. The upper is soft to the touch yet structured enough to provide a secure, sock-like feel, reducing irritation and hot spots even during extended wear. Brooks also improved the interior comfort with a plush tongue and collar, ensuring that every step feels luxurious. The shoe's smooth, more rounded heel design further enhances the transition from heel to toe, giving runners a fluid, natural stride that feels effortless regardless of pace.
Underfoot, the Glycerin 21 features a durable rubber outsole that balances traction and flexibility, allowing for confident grip on roads and light trail conditions alike. The shoe's aesthetic has also been elevated with sleek, modern colorways that appeal to both performance-driven athletes and everyday walkers seeking stylish comfort. Whether you're logging marathon training miles, transitioning from a workout to errands, or simply want a dependable everyday trainer that prioritizes cushioning and support, the Brooks Glycerin 21 stands out as a top-tier option in the running and fitness footwear category, blending cutting-edge cushioning technology with the reliable performance Brooks is known for.
Customer reviews
My knees thank me after every run. The DNA Loft v3 midsole is incredibly plush without feeling mushy or unstable.
Perfect for my easy and recovery runs. Not the shoe I'd race in, but for daily miles it's fantastic.
No break-in period needed. The upper is soft and breathable, and the fit is true to size with a roomy toe box.
Pricier than other trainers but the comfort and durability make it worthwhile for high weekly mileage.



